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Application Bibliography

Application
Area
Product
ReferenceDate

Imaging genotype and phenotype at single-cell resolution by sequencing cellular perturbation identity in situ.

High-Content Screening

CELESTA Light Engine, SOLA Light Engine

2022

Imaging of spectrally-encoded lanthanide nanoparticles (LNP)

Microfluidics

SOLA Light Engine

2022

Simultaneous visualization of 16 small (62–73 kb) DNA loci in G1 phase hTERT RPE-1 cells using single-molecule FISH

Fluorescence in Situ Hybridization (FISH)

SPECTRA Light Engine

2022

Identification of Parkinson’s disease-specific cellular phenotypes from high-content imaging datasets

High-Content Screening

SPECTRA X Light Engine

2022

Hybridization-based in situ sequencing (HybISS) via direct RNA detection for identifying low abundance transcripts in mouse brain sections

Transcriptomics

SPECTRA X Light Engine

2022

Optogenetic induction of telomere coalescence

Optogenetics

SPECTRA X Light Engine

2022

Quantitative immunofluorescence analysis of dystrophin expression in muscle biopsy tissue

Diagnostics

SOLA Light Engine

2022

Imaging of labeled mRNA transcripts for validation of probe hybridization

Transcriptomics

SPECTRA X Light Engine

2022

One-photon photostimulation of fast-acting, high-conductance ChroME2.0 opsins

Optogenetics

SPECTRA X Light Engine

2022

Evaluation of the photovoltaic effect in molybdenum disulfide (MoS2) semiconductor flakes

Materials Science

SOLA Light Engine

2022

340/380 nm fura-2 imaging of dysregulated Ca2+ homeostasis in mouse fibroblasts

Live Cell Microscopy

RETRA Light Engine

2022

Super-resolution radial fluctuation (SRRF) microscopy of chromatin

Superresolution Microscopy

SPECTRA Light Engine

2022

Quantitative immunofluorescence analysis of tropomyosin expression in mesenchymal stromal/stem cells (MSCs)

Immunofluorescence Microscopy

SPECTRA X Light Engine

2021

Image-based identification of CRISPR-induced phenotypes

High-Content Screening

SPECTRA X Light Engine

2021

Single-molecule RNA fluorescence in situ hybridization (smFISH) in Saccharomyces cerevisiae

Transcriptomics

SPECTRA X Light Engine

2021

Reflection interference contrast microscopy (RICM) of unlabeled microtubules.

Biophysics

SOLA Light Engine

2021

Detection of streptavidin-phycoerythrin (SAPE) fluorescence linked to hybridization of exosomal microRNAs on hydrogel microparticles

Diagnostics

SOLA Light Engine

2021

DNA FISH chromatin tracing correlated with immunofluorescence detection of epigenetic markers in IMR-90 cells

Transcriptomics

CELESTA Light Engine

2021

High-throughput neurite outgrowth analysis using organotypic explant cultures

High-Content Screening

SPECTRA X Light Engine

2021

Two-color immunofluorescence detection of SARS-CoV-2 spike protein localization on HEK293T cell membranes

Immunofluorescence Microscopy

SOLA Light Engine

2021

Ultraviolet photoactivation of NP-caged isopropyl ß-D-1-thiogalactopyranoside (IPTG)

Optogenetics

SOLA Light Engine

2021

Automated whole-slide scanning FISH analysis on formalin fixed, paraffin embedded (FFPE) specimens

Fluorescence in Situ Hybridization (FISH)

SPECTRA Light Engine

2021

Immunofluorescence detection of PI(4,5)P2 and lipid phosphatase synaptojanin1 in cultured mouse astrocytes

Immunofluorescence Microscopy

SPECTRA X Light Engine

2021

Imaging of lipid droplets in Drosophila larvae

Confocal Microscopy

CELESTA Light Engine

2021

Rapid fluorescence-based immunoassay for detection of viral pathogens including SARS-CoV-2

Diagnostics

SOLA Light Engine

2021