Application Bibliography
| Application | Area Product | Reference | Date |
|---|---|---|---|
Imaging T-cell calcium signaling elicited by a biomimetic antigen-presenting system (bAPS) | Bioengineering SPECTRA X Light Engine | 2024 | |
Confocal immunofluorescence localization of Aurora-A kinase (AurkA) and its major regulator TPX2 in hTERT RPE-1 cells | Confocal Microscopy CELESTA Light Engine | 2024 | |
Time-lapse imaging of periplasmic mTurquoise2 and cytoplasmic mCherry in Escherichia coli | Microbiology SOLA Light Engine | SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains. Nature (2024) 626:617–625 A Janssens, VS Nguyen, H Remaut et al. | 2024 |
Immunofluorescence identification of metastatic prostate cancer cells based on epithelial cell adhesion molecule (EpCAM) expression | Diagnostics SOLA Light Engine | A magnetic microneedle to isolate single immunomagnetically labeled cells. Lab Chip (2024) 24:460–466 M Stevens, P Harder, LWMM Terstappen | 2024 |
Imaging laminar flow of peripheral blood mononuclear cells (PBMC) and neutrophils during microfluidic acoustophoresis | Microfluidics CELESTA Light Engine | Label‐free separation of peripheral blood mononuclear cells from whole blood by gradient acoustic focusing. Sci Rep (2024) 14:8748 J Alsved, MR Charan, P Augustsson et al. | 2024 |
Imaging fission and fusion of neuronal mitochondria expressing photoactivatable GFP (paGFP) and mScarlet | Live Cell Microscopy AURA Light Engine | 2024 | |
In situ sequencing (ISS) for single-cell spatial expression profiling of the spatiotemporal cellular dynamics underlying autoimmune encephalomyelitis (EAE) evolution. | Transcriptomics SPECTRA X Light Engine | Cellular architecture of evolving neuroinflammatory lesions P Kukanja, CM Langseth, G Castelo-Branco et al. | 2024 |
Real-time measurement of polymer–nucleotide substrate (avidite) binding to DNA polonies | Genomic Analysis RETRA Light Engine | Sequencing by avidity enables high accuracy with low reagent consumption. Nat Biotechnol (2024) 42:132–138 S Arslan, FJ Garcia, M Previte et al. | 2024 |
Immunofluorescence detection of long myosin light-chain kinase (MLCK) splice variants in FFPE ileal tissue microarrays from Crohn’s disease patients. | Pathology SOLA Light Engine, AURA Light Engine | 2024 | |
Imaging intracellular neuropeptide concentrations using a genetically encoded sensor comprising vasoactive intestinal peptide receptor VPAC1 coupled to circularly permuted GFP | Pathology SPECTRA Light Engine, SPECTRA X Light Engine | Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature (2024) 627:149–156 MH Murdock, CY Yang, LH Tsai et al. | 2024 |
Vesicular glutamate transporter 1 (VGLUT1) mRNA FISH for identification and somal size measurement of human brain pyramidal neurons (PNs) | Fluorescence in Situ Hybridization (FISH) SPECTRA Light Engine | Scaling of smaller pyramidal neuron size and lower energy production in schizophrenia. Neurobiol Dis (2024) 191:106394 KE Schoonover, NE Miller, D Lewis et al. | 2024 |
Tracing interactions of polycomb group (PcG) proteins with chromatin by Optical Reconstruction of Chromatin Architecture (ORCA) | Transcriptomics CELESTA Light Engine | 2024 | |
Colocalization of antisense oligonucleotides and proteins using widefield 3D deconvolution microscopy | Immunofluorescence Microscopy AURA Light Engine | Profiling the interactome of oligonucleotide drugs by proximity biotinylation. Nat Chem Biol (2024) doi: 10.1038/s41589-023-01530-z A Hanswillemenke, DT Hofacker, T Stafforst | 2024 |
Structured illumination microscopy with 100 nm lateral and 300 nm axial resolution | Superresolution Microscopy CELESTA Light Engine | Easy access to super-resolution applications with DeepSIM. Microscopy Today (2024) 32, 10–15 C Brighi, L Clario, S Romanzi | 2024 |
Live-cell imaging for assessment of bacterial phenotype after antibiotic treatment | Microbiology SOLA Light Engine | 2024 | |
Two-color fluorescence imaging of E. coli and titanium dioxide (TiO2) nanowires | Environmental Science SOLA Light Engine | 2023 | |
Identification of fibroblast lineages in embryonic mouse skin via single-molecule FISH and immunofluorescence imaged with the X-Light V3 spinning disk confocal | Confocal Microscopy CELESTA Light Engine | Molecular and spatial landmarks of early mouse skin development. Dev Cell T Jacob, K Annusver, M Kasper et al. | 2023 |
1) Photoactivation of ChR2 (467–499 nm) and ACR1 (500–550 nm) in C. elegans. (2) Excitation of genetically encoded fluorescent calcium indicators and jRGECO1a and GCaMP. | Optogenetics SOLA Light Engine, SPECTRA X Light Engine | Neural engineering with photons as synaptic transmitters. Nat Methods M Porta-de-la-Riva, AC Gonzalez, M Krieg et al. | 2023 |
Imaging of calcium transients and action potentials in stem cell-derived microheart muscles | Bioengineering AURA Light Engine | 2023 | |
Excitation of Janelia Fluor 570 (JF570) for photosensitization of diaminobenzidine (DAB) oxidation | Multimode Imaging SPECTRA Light Engine | 2023 | |
Imaging of lipofuscin and melanin in mouse retinal pigment epithelium (RPE) | Pathology SOLA Light Engine | Chemiexcitation and melanin in photoreceptor disc turnover and prevention of macular degeneration. Proc Natl Acad Sci U S A (2023) 120:e2216935120 Y Lyu, AV Tschulakow, U Schraermeyer et al. | 2023 |
Spatial transcriptomic profiling of mouse brain using electrophoretically enhanced smFISH | Transcriptomics SPECTRA Light Engine | Scalable in situ single-cell profiling by electrophoretic capture of mRNA using EEL FISH. Nat Biotechnol (2023) 41:222–231 LE Borm, AM Albiach, S Linnarsson et al. | 2023 |
Immunofluorescence detection of anti-inflammatory CD8+ T cells in proximity to plaque-associated microglia in human and mouse Alzheimer’s disease brain tissue | Pathology SOLA Light Engine | 2023 | |
Single cell measurements of secreted antibody affinity for the SARS-CoV-2 spike receptor binding domain | Microfluidics AURA Light Engine | 2023 | |
Illuminatation (650 nm, 34 mW/cm2) of phosphorus-doped silicon (p–Si) photoelectrodes. | Materials Science SPECTRA Light Engine | 2023 |