SPECTRA Light Engine
The next generation of solid-state illumination is here. In Lumencor’s SPECTRA Light Engine, eight individually addressable solid-state light sources deliver unprecedented performance. Each color band provides on the order of a half a watt of optical power at the distal end of a 3 mm liquid light guide. The constituent light sources include LEDs, Lumencor’s proprietary luminescent light pipes and lasers. The outputs of the sources are refined by bandpass filters and merged into a common optical train directed to the light output port on the front panel. The light output port has a built-in adapter for connection to microscopes and other bioanalytical instruments through a standard, 3 mm diameter liquid light guide. TTL trigger inputs are provided for all eight illumination sources for applications requiring fast output switching.
"Lumencor’s SPECTRA Light Engine “kicks butt” on our expensive microscope."
George McNamara, Manager of the Ross Fluorescence Imaging Core, Johns Hopkins University
Application Bibliography
| Application | Area Product | Reference | Date |
|---|---|---|---|
Six-color confocal phenotypic imaging of CRISPR–Cas9 knockouts in HUVEC cells | High-Content Screening SPECTRA Light Engine | 2024 | |
Total internal reflection fluorescence (TIRF) microscopy of Ca2+ dynamics and granule fusions in insulin-secreting INS-1 cells | Live Cell Microscopy SPECTRA Light Engine | 2024 | |
Imaging intracellular neuropeptide concentrations using a genetically encoded sensor comprising vasoactive intestinal peptide receptor VPAC1 coupled to circularly permuted GFP | Pathology SPECTRA Light Engine, SPECTRA X Light Engine | Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature (2024) 627:149–156 MH Murdock, CY Yang, LH Tsai et al. | 2024 |
Vesicular glutamate transporter 1 (VGLUT1) mRNA FISH for identification and somal size measurement of human brain pyramidal neurons (PNs) | Fluorescence in Situ Hybridization (FISH) SPECTRA Light Engine | Scaling of smaller pyramidal neuron size and lower energy production in schizophrenia. Neurobiol Dis (2024) 191:106394 KE Schoonover, NE Miller, D Lewis et al. | 2024 |