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Application Bibliography

Application
Area
Product
ReferenceDate

Label-free optical redox imaging (ORI) for monitoring human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) differentiation and maturation

High-Content Screening

SOLA Light Engine

2024

Imaging of membrane potential in rat hippocampal neurons using the genetically encoded fluorescent voltage indicator ASAP3β

Live Cell Microscopy

SOLA Light Engine

2024

High-throughput in situ sequencing interrogation of the expression of 104 cell-type marker genes at cellular resolution in the mouse cerebral cortex.

Transcriptomics

CELESTA Light Engine

2024

Total internal reflection fluorescence (TIRF) microscopy of Ca2+ dynamics and granule fusions in insulin-secreting INS-1 cells

Live Cell Microscopy

SPECTRA Light Engine

2024

Iterative indirect immunofluorescence imaging (4i) of retinoblastoma (Rb) phosphorylation in MCF-10A human mammary epithelial cells

Immunofluorescence Microscopy

SPECTRA X Light Engine

2024

Multiplexed immunofluorescence imaging on large (average area = 0.25 mm2) sections of healthy, regenerating, and embolized human liver tissues

Immunofluorescence Microscopy

CELESTA Light Engine

2024

Cryo-fluorescence microscopy detection of MX04-labeled amyloid in postmortem Alzheimer’s disease brain tissue

Pathology

SOLA Light Engine

2024

Optical control of protein dimerization via reversible photoisomerization of an azobenzene ligand

Optogenetics

SPECTRA X Light Engine

2024

Time-lapse confocal spinning disk imaging of heterotypic human ovarian fibroblast + serous ovarian cancer spheroid invasion of mesothelial cell monolayers

Confocal Microscopy

CELESTA Light Engine

2024

Imaging T-cell calcium signaling elicited by a biomimetic antigen-presenting system (bAPS)

Bioengineering

SPECTRA X Light Engine

2024

Confocal immunofluorescence localization of Aurora-A kinase (AurkA) and its major regulator TPX2 in hTERT RPE-1 cells

Confocal Microscopy

CELESTA Light Engine

2024

Time-lapse imaging of periplasmic mTurquoise2 and cytoplasmic mCherry in Escherichia coli

Microbiology

SOLA Light Engine

2024

Immunofluorescence identification of metastatic prostate cancer cells based on epithelial cell adhesion molecule (EpCAM) expression

Diagnostics

SOLA Light Engine

2024

Imaging laminar flow of peripheral blood mononuclear cells (PBMC) and neutrophils during microfluidic acoustophoresis

Microfluidics

CELESTA Light Engine

2024

Imaging fission and fusion of neuronal mitochondria expressing photoactivatable GFP (paGFP) and mScarlet

Live Cell Microscopy

AURA Light Engine

2024

In situ sequencing (ISS) for single-cell spatial expression profiling of the spatiotemporal cellular dynamics underlying autoimmune encephalomyelitis (EAE) evolution.

Transcriptomics

SPECTRA X Light Engine

2024

Real-time measurement of polymer–nucleotide substrate (avidite) binding to DNA polonies

Genomic Analysis

RETRA Light Engine

2024

Immunofluorescence detection of long myosin light-chain kinase (MLCK) splice variants in FFPE ileal tissue microarrays from Crohn’s disease patients.

Pathology

SOLA Light Engine, AURA Light Engine

2024

Imaging intracellular neuropeptide concentrations using a genetically encoded sensor comprising vasoactive intestinal peptide receptor VPAC1 coupled to circularly permuted GFP

Pathology

SPECTRA Light Engine, SPECTRA X Light Engine

2024

Vesicular glutamate transporter 1 (VGLUT1) mRNA FISH for identification and somal size measurement of human brain pyramidal neurons (PNs)

Fluorescence in Situ Hybridization (FISH)

SPECTRA Light Engine

2024

Tracing interactions of polycomb group (PcG) proteins with chromatin by Optical Reconstruction of Chromatin Architecture (ORCA)

Transcriptomics

CELESTA Light Engine

2024

Colocalization of antisense oligonucleotides and proteins using widefield 3D deconvolution microscopy

Immunofluorescence Microscopy

AURA Light Engine

2024

Structured illumination microscopy with 100 nm lateral and 300 nm axial resolution

Superresolution Microscopy

CELESTA Light Engine

2024

Live-cell imaging for assessment of bacterial phenotype after antibiotic treatment

Microbiology

SOLA Light Engine

2024

Simultaneous 473 nm photstimulation of ChR2 and 585 nm excitation of genetically encoded voltage indicator Voltron fluorescence in murine acute brain slices.

Optogenetics

SPECTRA X Light Engine

2023