RETRA Light Engine
The RETRA Light Engine incorporates two individually controllable solid-state light sources with associated bandpass filters, producing spectrally discrete outputs. Spectral outputs can be situated from the ultraviolet through the visible to the near-infrared, according to application-specific requirements. As one example, the RETRA FURA Light Engine provides 340 nm and 380 nm outputs for fura-2 ratio calcium imaging.
Frequently Asked Questions
"Lumencor Light Engines provide strong light intensity, a fairly uniform field, and many wavelengths. This allows us to quantify more samples in more colors, faster."
Johan Paulsson, Professor of Systems Biology, Harvard Medical School
Application Bibliography
| Application | Area Product | Reference | Date |
|---|---|---|---|
Fura-2 intracellular calcium imaging of DRG neurons | Live Cell Microscopy RETRA Light Engine | A γδ T cell-IL-3 axis controls allergic responses through sensory neurons. Nature (2024) 634:440–446 CH Flayer, IJ Kernin, CL Sokol et al. | 2024 |
Real-time measurement of polymer–nucleotide substrate (avidite) binding to DNA polonies | Genomic Analysis RETRA Light Engine | Sequencing by avidity enables high accuracy with low reagent consumption. Nat Biotechnol (2024) 42:132–138 S Arslan, FJ Garcia, M Previte et al. | 2024 |
550 nm illumination of hybrid perovskite films for characterization of degradation pathways | Materials Science RETRA Light Engine | Water-accelerated photooxidation of CH3NH3PbI3 perovskite. J Am Chem Soc (2022) 144:5552–5561 TD Siegler, WA Dunlap-Shohl, HW Hillhouse et al. | 2022 |
340/380 nm fura-2 imaging of dysregulated Ca2+ homeostasis in mouse fibroblasts | Live Cell Microscopy RETRA Light Engine | 2022 |