Application Bibliography
| Application | Area Product | Reference | Date |
|---|---|---|---|
Photostimulation (470 nm, 30 mW/mm2) of Ziapin2 in human induced pluripotent stem cell-derived cardiomyocytes | Optogenetics SPECTRA X Light Engine | 2023 | |
Optogenetic inhibition using 513 nm light-gated potassium channels (kalium channelrhodopsins) in acute mouse brain slices | Optogenetics SPECTRA X Light Engine | All-optical physiology resolves a synaptic basis for behavioral timescale plasticity. Cell (2023) 186:543–559 LZ Fan, DK Kim, K Deisseroth et al. | 2023 |
Mapping of cellular heterogeneity in the developing human lung using hybridization-based in situ sequencing (HybISS) | Transcriptomics SPECTRA X Light Engine | A topographic atlas defines developmental origins of cell heterogeneity in the human embryonic lung. Nat Cell Biol (2023) 25:351–365 A Sountoulidis, SM Salas, C Samakovlis et al. | 2023 |
Fluorescence microscopy analysis of oral squamous cell carcinoma cell response to immunotherapy | Diagnostics SOLA Light Engine | 2023 | |
Time-lapse confocal analysis of ovarian cancer cell spheroid attachment to mesothelial monolayers | Confocal Microscopy CELESTA Light Engine | 2023 | |
400 and 480 nm excitation of dLight1.1 dopamine sensor in the dorsolateral striatum (DLS) of freely moving mice | Intravital Imaging AURA Light Engine | Spontaneous behaviour is structured by reinforcement without explicit reward. Nature (2023) 614:108–117 JE Markowitz, WF Gillis, SR Datta et al. | 2023 |
Photoelectrochemical (PEC) hydrogen generation in a particle suspension reactor (PSR). | Photochemistry SPECTRA X Light Engine | Water splitting with silicon p-i-n superlattices suspended in solution. Nature (2023) 614:270–274 TS Teitsworth, DJ Hill, JF Cahoon et al. | 2023 |
MERFISH imaging of cellular organization during mouse brain aging | Transcriptomics CELESTA Light Engine | Molecular and spatial signatures of mouse brain aging at single-cell resolution. Cell (2023) 186:194–208 WE Allen, TR Blosser, X Zhuang et al. | 2023 |
Super-resolved stimulated Raman scattering (SRS) imaging for measurement of nanoscopic biomolecualr colocalization and metabolic dynamics in organelles | Superresolution Microscopy CELESTA Light Engine | Super-resolution SRS microscopy with A-PoD. Nat Methods (2023) 20:448–458 H Jang, Y Li, L Shi et al. | 2023 |
Fura-2 Ca2+ imaging in mouse pituitary cells | Live Cell Microscopy RETRA Light Engine | Common and female‐specific roles of protein tyrosine phosphatase receptors N and N2 in mice reproduction. Sci Rep (2023) 13:355 SJ Sokanovic, S Constantin, SS Stojilkovic et al. | 2023 |
Single-particle tracking (SPT) of 100-nm microspheres in Xenopus laevis egg extracts | Biophysics SPECTRA Light Engine | 2022 | |
Imaging of chitin stained with Calcofluor White M2R | Microscopy Technique Development SOLA Light Engine | 2022 | |
Identification of genes controlling genome integrity, cytoskeletal organization and cell division by pooled image-based screening | High-Content Screening CELESTA Light Engine | The phenotypic landscape of essential human genes. Cell (2022) 185:4634–4653 L Funk, KC Su, IM Cheeseman et al. | 2022 |
Immunofluorescence determination of total, proinflammatory, and proliferating macrophage density in duodenal cryosections from 18-days-old post-hatch broiler chickens | Immunofluorescence Microscopy SOLA Light Engine | 2022 | |
Imaging of GFP-cyclin-dependent kinase (CDK) and mitotic CDK activity biosensor, synCut3–mCherry in Schizosaccharomyces pombe fission yeast | Live Cell Microscopy SPECTRA X Light Engine | Core control principles of the eukaryotic cell cycle. Nature (2022) 607:381–386 S Basu, J Greenwood, P Nurse et al. | 2022 |
Reflection interference contrast microscopy (RICM) of ST6Gal-I overexpressing Cos-7 cells | Biophysics SOLA Light Engine | 2022 | |
Label-free interference reflection microscopy (IRM) of microtubules | Biophysics SOLA Light Engine | 2022 | |
Imaging of spectrally-encoded lanthanide nanoparticles (LNP) | Microfluidics SOLA Light Engine | 2022 | |
Imaging genotype and phenotype at single-cell resolution by sequencing cellular perturbation identity in situ. | High-Content Screening CELESTA Light Engine, SOLA Light Engine | Pooled genetic perturbation screens with image-based phenotypes. Nat Protoc (2022) 17:476–512 D Feldman, L Funk, PC Blainey et al. | 2022 |
550 nm illumination of hybrid perovskite films for characterization of degradation pathways | Materials Science RETRA Light Engine | Water-accelerated photooxidation of CH3NH3PbI3 perovskite. J Am Chem Soc (2022) 144:5552–5561 TD Siegler, WA Dunlap-Shohl, HW Hillhouse et al. | 2022 |
Simultaneous visualization of 16 small (62–73 kb) DNA loci in G1 phase hTERT RPE-1 cells using single-molecule FISH | Fluorescence in Situ Hybridization (FISH) SPECTRA Light Engine | Simultaneous visualization of DNA loci in single cells by combinatorial multi-color iFISH. Sci Data (2022) 9:47 A Mota, M Schweitzer, M Bienko et al. | 2022 |
Identification of Parkinson’s disease-specific cellular phenotypes from high-content imaging datasets | High-Content Screening SPECTRA X Light Engine | 2022 | |
Hybridization-based in situ sequencing (HybISS) via direct RNA detection for identifying low abundance transcripts in mouse brain sections | Transcriptomics SPECTRA X Light Engine | Direct RNA targeted in situ sequencing for transcriptomic profiling in tissue. Sci Rep (2022) 12:7976 H Lee, SM Salas, M Nilsson et al. | 2022 |
Optogenetic induction of telomere coalescence | Optogenetics SPECTRA X Light Engine | Compartmentalization of telomeres through DNA- scaffolded phase separation. Dev Cell (2022) 57:277–290 A Jack, Y Kim, CP Brangwynne et al. | 2022 |
Quantitative immunofluorescence analysis of dystrophin expression in muscle biopsy tissue | Diagnostics SOLA Light Engine | 2022 |