Visit Lumencor at Booth #333 at the ASCB Annual Meeting, hosted at Moscone Center in San Francisco, California – December 3-7, 2016.
Lumencor’s lighting products represent the industry’s brightest, fastest and most stable illuminators. Off-the-shelf and custom products for fluorescence and transmitted light microscopy and a host of life science applications are on display at this exhibit. All of our products are simple to use, energy efficient and mercury free.
Drop by the booth or make an appointment to talk with our talented technical support, sales and business development staff.
AURA Light Engine® for Ca2+ Ratio Imaging
Fluorescence excitation spectra of fura-8 Ca2+ indicator showing 360/28 nm and 395/25 nm excitation bandpasses supplied by Lumencor’s AURA light engine
Ratio imaging of intracellular calcium has long been an important technique in cell biology, neuroscience and related fields. Excitation ratio imaging compensates for variations of indicator dye concentration within cells and between cells that might otherwise be interpreted as calcium level changes.
The preferred indicator dyes for Ca2+ ratio imaging are typically fura-2 and the recently developed red-shifted analog fura-8. Excitation ratio imaging is conventionally implemented using a white light source in combination with mechanically alternated filters to select the desired excitation wavelengths (340 and 380 nm for fura-2, 360 and 400 nm for fura-8).
Lumencor’s AURA light engine generates these excitation outputs from two discrete electronically controlled solid-state light sources. The AURA light engine can accommodate up to five sources, providing additional outputs for optogenetics or GFP/mCherry excitation.
Our RETRA light engine can be configured with 360/28 nm and 395/25 nm outputs for customers requiring a dedicated two-channel excitation source. Electronic alternation of excitation wavelengths provided by AURA or RETRA light engines is faster and more reproducible than mechanical methods. In turn, this allows higher-speed data acquisition, providing increased temporal resolution for recording elementary processes in cell physiology.
For further information, download our calcium ratio imaging application note.
Download the PDF of Light BYTES: December 2016.
Lumencor, Inc., an industry leader in the photonics market for the life sciences, is proud to announce that the company recently received their certificate of registration to ISO 13485:2003.
“We are pleased that Lumencor has just been ISO 13485:2003 certified by the British Standards Institution (BSI) for the design, development, manufacture, distribution and servicing of light engines and high throughput scanners,” stated Claudia Jaffe, Ph.D., Executive Vice President of Business Development. “This achievement is one that we are particularly proud of as it demonstrates our commitment to providing the highest quality products and services to our customers. It further establishes Lumencor as a leader in the life sciences for the manufacture of tools for bioanalysis as well as for medical devices.”
ISO 13485:2003 is the internationally recognized standard which specifies requirements for a comprehensive quality management system in which an organization needs to demonstrate its ability to provide medical devices and related services that consistently meet customer and applicable regulatory requirements.
Read the full Press Release
It All Begins With Illumination
Be sure to mark your calendar as busy on November 12-16: they’re the official dates for Neuroscience 2016.
Light microscopy and optogenetics start with the light source. Make sure you start with the source at Neuroscience 2016, and head to booth #818 to see the best-in-show solid state illuminators. These lighting products are today’s industry leaders in terms of brightness, speed and both short and long term stability.
Here’s a preview of some of the products we’ll have at the show:
AURA LIGHT ENGINE®
- 360 nm/390 nm fast excitation switching for ratiometric Ca2+ imaging
- >100 mW fiber output at 475 nm and 560 nm for ChR2 and NpHR photostimulation
- Liquid light guide or optical fiber output coupling
SPECTRA X LIGHT ENGINE®
- Integrated array of six powerful solid-state light sources
- Spectral output refined by user-exchangeable filters
- Near IR (710–750 nm) output option for intravital imaging
- Individual source selection and intensity control from image acquisition software or control pod accessory
LIDA LIGHT ENGINE®
- RGB color transmitted light imaging with monochrome cameras
- 1 kHz RGB channel switching or continuous white light for ocular viewing
- Direct mount to transmitted light port of major brand microscopes
To see the best solid state light sources, visit Lumencor at booth #818 and speak with our talented technical support and sales staff.
See you in San Diego!